Volume 3, Issue 1, March 2018, Page: 6-11
Morphology Transformation of Giant Vesicles by a Polyelectrolyte for an Artificial Model of a Membrane Protein for Endocytosis
Eri Yoshida, Department of Environmental and Life Sciences, Toyohashi University of Technology, Toyohashi, Japan
Received: Feb. 20, 2018;       Accepted: Mar. 6, 2018;       Published: Mar. 23, 2018
DOI: 10.11648/j.css.20180301.12      View  869      Downloads  38
Abstract
The morphology transformation of giant vesicles consisting of amphiphilic poly(methacrylic acid)- block-poly(methyl methacrylate-random-methacrylic acid-random-3-sulfopropyl methacrylate potassium salt), PMAA-b-P(MMA-r-MAA-r-SpMA), was investigated using poly(allylamine hydrochloride) (PAH) as an artificial model of a membrane protein for endocytosis. The polymerization-induced self-assembly of the PMAA-b-P(MMA-r-MAA-r-SpMA) using the nitroxide-mediated photo-controlled/living radical polymerization technique produced spherical vesicles in the absence of PAH, while it provided a fused sheet in its presence at a 1.0 molar ratio of the allylamine hydrochloride unit (AH) to the SpMA unit. It was suggested that the PAH connected the SpMA units by an electrostatic interaction. The fused sheet changed into combined vesicles as the AH/SpMA ratio increased, and at AH/SpMA = 10.0, the morphology was transformed into spherical vesicles much smaller than the original vesicles. The morphology transformation by soaking the original spherical vesicles in a PAH solution demonstrated that the PAH caused the division of the vesicles into much smaller spherical vesicles.
Keywords
Giant Vesicles, Amphiphilic Diblock Copolymer, Photo NMP-Induced Self-assembly, Morphology Transformation, Vesicle Division, Polyelectrolyte, Electrostatic Interaction
To cite this article
Eri Yoshida, Morphology Transformation of Giant Vesicles by a Polyelectrolyte for an Artificial Model of a Membrane Protein for Endocytosis, Colloid and Surface Science. Vol. 3, No. 1, 2018, pp. 6-11. doi: 10.11648/j.css.20180301.12
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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